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Oh Hyunrim |
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Research Engineer
Biomagnetics Laboratory (BML)
Phone:
(65) 6516-1496
Advisors:
Assist Prof. Bae, Seongtae
A Member
of
Biomagnetics Laboratory (BML)
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My name is Oh, Hyunrim from Korea. I worked to find new active compounds for drug discovery (HCV, HIV, Leishmania) through High Throughput/Content Screening (HT/CS). I am doing research on magnetic nanoparticles for tumor therapy and its medical application.
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Thesis
Development of medical application system of magnetic nanoparticles for cancer therapy
Research
Interests
Tumor targeted nanoparticles for drug delivery
system
Combination of drug and nanoparticles to enhance therapeutic efficacy
Multifunctional Nanoparticles for Cancer diagnosis and imaging
Controlling the biodistribution in location and time
Publications
Siqueira-Neto JL#, Song O-R#, Oh H#, Sohn J-H, Yang G, et al. "Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds", PLoS Negl Trop Dis, 4(5), e675
(2010)
# These authors contributed equally to this work.
Oh HL, Seok JY, Kwon CH, Kang SK, Kim YK.
"Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain", Neurotoxicology,
27(1), 31 (2006)
Lee WC, Choi CH, Cha SH, Oh HL, Kim- YK. "Role of ERK in hydrogen peroxide-induced cell death of human glioma cells", Neurochem Res.,
30(2), 263 (2005)
Choi, B.K., Choi, C.H., Oh, H.L., Kim, Y.K. "Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells", Neurotoxicology, 25(6), 915
(2004)
Awards and Scholarships
Brain Korea 21 program scholarship
Work Experience
Researcher, Institut Pasteur Korea [Dec. 2005- March. 2011]
- Drug discovery through High Throughput/Content Screening (HT/CS)
Conference
"Drug
discovery in Leishmania", Hyunrim Oh, Okryul Song, Jair Lage Siqueira Neto, Arnaud Ogier, Auguste Genovesio, Thierry Christophe, Lucio Freitas-Junior,
The Korean
Journal of Parasitology (2007)
"Development
of a cell-based high throughput screening for drugs affecting Plasmodium falciparum var
genes regulation", Fernando M. Dossin, Hyunrim Oh, Musa M. Mhlanga, Auguste Genovesio, Thierry Christophe, Lucio Freitas-Junior, The Journal of Parasitology
(2006)
"Cell proliferation and activation of survival signaling pathways by
hypoxia/reoxygenation in renal epithelial cells", Kwon, C.H., OH, H.L., Kim Y.K,
The Korean Journal of Physiology & Pharmacology (2004)
"Role of ERK activation in cisplatin-induced apoptosis in renal epithelial
cells", Kwon, C.H., OH, H.L., Kim Y.K., The Hong Kong international Journal of
Nephrology (2004)
"Modulation of cisplatin-induced apoptosis by MAPK signalling in renal proximal epithelial cells", Kwon, C.H., OH, H.L., Kim Y.K, The Korean Journal of Nephrology (2003).
"Physical Parameters to Enhance AC Heating Characteristics of Superpara- and Ferri-Magnetic Nanoparticles for Local Hyperthermia",
Minhong Jeun, Sanghoon Lee, Hyunrim Oh, Yu Jeong Kim, Ki Ho Park, Sun Ha Paek, Yasushi Takemura, Kyung-Won Chung, Jiyeon Kwak, Seongtae Bae
[ES-01] 56th MMM International Conference, Arizona, Scottsdale, USA (2011, Oct. 30 ~ Nov. 3)
"Physical Limits of Pure Superparamagnetic Fe3O4 Nanoparticles for a Local Hyperthermia Agent in Nanomedicine",
Minhong Jeun, Sanghoon Lee, Hyunrim Oh, Ashahi Tomitaka, Yasushi Takemura, Kyung-Won Chung, Young Il Kim, Keon Wook Kang, Jiyeon Kwak, Seongtae Bae
[ES-04] 56th MMM International Conference, Arizona, Scottsdale, USA (2011, Oct. 30 ~ Nov. 3)
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